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Combination chemoprevention of HER2/neu-induced breast cancer using a COX-2 inhibitor and an RXR-selective retinoid

The inducible prostaglandin synthase isoform cyclooxygenase-2 (COX-2) is overexpressed in ~40% of human breast carcinomas, and in precancerous breast lesions, particularly in association with overexpression of human epidermal growth factor receptor 2 (HER2/neu). Experimental breast cancer can be sup...

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Detalhes bibliográficos
Main Authors: Brown, Powel H., Subbaramaiah, Kotha, Salmon, Amoi P., Baker, Rebecca, Newman, Robert A., Yang, Peiying, Zhou, Xi Kathy, Bissonnette, Reid P., Dannenberg, Andrew J., Howe, Louise R.
Formato: Artigo
Idioma:English
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612594/
https://ncbi.nlm.nih.gov/pubmed/19138958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-08-0021
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