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Restorative effect of endurance exercise on behavioral deficits in the chronic mouse model of Parkinson's disease with severe neurodegeneration

BACKGROUND: Animal models of Parkinson's disease have been widely used for investigating the mechanisms of neurodegenerative process and for discovering alternative strategies for treating the disease. Following 10 injections with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP, 25 mg/kg) an...

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Detalhes bibliográficos
Main Authors: Pothakos, Konstantinos, Kurz, Max J, Lau, Yuen-Sum
Formato: Artigo
Idioma:English
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640401/
https://ncbi.nlm.nih.gov/pubmed/19154608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-10-6
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