Improved Learning and Memory in Aged Mice Deficient in Amyloid β-Degrading Neutral Endopeptidase

BACKGROUND: Neutral endopeptidase, also known as neprilysin and abbreviated NEP, is considered to be one of the key enzymes in initial human amyloid-β (Aβ) degradation. The aim of our study was to explore the impact of NEP deficiency on the initial development of dementia-like symptoms in mice. METH...

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Detalhes bibliográficos
Main Authors: Walther, Thomas, Albrecht, Doris, Becker, Matthias, Schubert, Manja, Kouznetsova, Elena, Wiesner, Burkard, Maul, Björn, Schliebs, Reinhard, Grecksch, Gisela, Furkert, Jens, Sterner-Kock, Anja, Schultheiss, Heinz-Peter, Becker, Axel, Siems, Wolf-Eberhard
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643003/
https://ncbi.nlm.nih.gov/pubmed/19240795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004590
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2643003/
https://ncbi.nlm.nih.gov/pubmed/19240795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004590

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