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Live Borrelia burgdorferi Spirochetes Elicit Inflammatory Mediators from Human Monocytes via the Toll-Like Receptor Signaling Pathway

We investigated the mechanisms that lead to the production of proinflammatory mediators by human monocytes when these cells are exposed in vitro to live Borrelia burgdorferi spirochetes. We first focused on myeloid differentiation primary response protein 88 (MyD88), an adapter molecule that is esse...

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Detalhes bibliográficos
Main Authors: Dennis, Vida A., Dixit, Saurabh, O'Brien, Shannon M., Alvarez, Xavier, Pahar, Bapi, Philipp, Mario T.
Formato: Artigo
Idioma:English
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643645/
https://ncbi.nlm.nih.gov/pubmed/19139200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01078-08
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