Endogenous S-Nitrosoglutathione Modifies 5-Lipoxygenase Expression in Airway Epithelial Cells

S-Nitrosoglutathione (GSNO) is an endogenous bronchodilator with several beneficial pulmonary effects. Levels are decreased in the asthmatic airway, and GSNO inhalation has been proposed as an asthma therapy. 5-lipoxygenase (5-LO) is the rate-limiting enzyme in the synthetic pathway for cysteinyl le...

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Detalhes bibliográficos
Main Authors: Zaman, Khalequz, Hanigan, Marie H., Smith, Alison, Vaughan, John, Macdonald, Timothy, Jones, David R., Hunt, John F., Gaston, Benjamin
Formato: Artigo
Idioma:English
Publicado em: American Thoracic Society 2006
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644202/
https://ncbi.nlm.nih.gov/pubmed/16415251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0336RC
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2644202/
https://ncbi.nlm.nih.gov/pubmed/16415251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0336RC

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