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A Z-DNA sequence reduces slipped-strand structure formation in the myotonic dystrophy type 2 (CCTG)·(CAGG) repeat
All DNA repeats known to undergo expansion leading to human neurodegenerative disease can form one, or several, alternative conformations, including hairpin, slipped strand, triplex, quadruplex, or unwound DNA structures. These alternative structures may interfere with the normal cellular processes...
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| Autors principals: | , , , |
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| Format: | Article |
| Idioma: | English |
| Publicat: |
National Academy of Sciences
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651351/ https://ncbi.nlm.nih.gov/pubmed/19218442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807699106 |
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