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Source of Phosphate in the Enzymic Reaction as a Point of Distinction among Aminoglycoside 2″-Phosphotransferases

Aminoglycoside 2″-phosphotransferases are clinically important enzymes that cause high levels of resistance to aminoglycoside antibiotics by the organisms that harbor them. These enzymes phosphorylate aminoglycosides, and the modified antibiotics show significant reduction in the binding ability to...

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Detalhes bibliográficos
Main Authors: Toth, Marta, Chow, Joseph W., Mobashery, Shahriar, Vakulenko, Sergei B.
Formato: Artigo
Idioma:English
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652286/
https://ncbi.nlm.nih.gov/pubmed/19158087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808148200
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