Temporal dynamics of a predominant protease-inhibitor resistance mutation in a treatment naïve HCV-infected individual

The dramatic antiviral activities of drugs that specifically inhibit hepatitis C virus replication can be tempered by baseline mutations that confer resistance. We describe in an HIV-1/HCV coinfected individual the kinetics of an R155K mutation in HCV NS3 protease known to confer resistance to speci...

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Hlavní autoři: Kim, Arthur Y., Timm, Joerg, Nolan, Brian E., Reyor, Laura L, Kane, Katherine, Berical, Andrew C., Zachary, Kimon C., Lauer, Georg M., Kuntzen, Thomas, Allen, Todd M.
Médium: Článek
Jazyk:English
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653266/
https://ncbi.nlm.nih.gov/pubmed/19199553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/596657
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2653266/
https://ncbi.nlm.nih.gov/pubmed/19199553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/596657

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