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Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly-made proteins with complex topologies
Folding within the crowded cellular milieu often requires assistance from molecular chaperones that prevent inappropriate interactions leading to aggregation and toxicity. The contribution of individual chaperones to folding the proteome remains elusive. We here demonstrate that the eukaryotic chape...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2658641/ https://ncbi.nlm.nih.gov/pubmed/19011634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1515 |
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