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Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis

Pleckstrin, the platelet and leukocyte C kinase substrate, is a prominent substrate of PKC in platelets, monocytes, macrophages, lymphocytes, and granulocytes. Pleckstrin accounts for 1% of the total protein in these cells, but it is best known for containing the 2 prototypic Pleckstrin homology, or...

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Detalhes bibliográficos
Main Authors: Lian, Lurong, Wang, Yanfeng, Flick, Matthew, Choi, John, Scott, Edward W., Degen, Jay, Lemmon, Mark A., Abrams, Charles S.
Formato: Artigo
Idioma:English
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668855/
https://ncbi.nlm.nih.gov/pubmed/19190246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-09-178913
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