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Mutations in the Insulin-Like Factor 3 Receptor Are Associated With Osteoporosis

INTRODUCTION: Insulin-like factor 3 (INSL3) is produced primarily by testicular Leydig cells. It acts by binding to its specific G protein–coupled receptor RXFP2 (relaxin family peptide 2) and is involved in testicular descent during fetal development. The physiological role of INSL3 in adults is no...

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Detalhes bibliográficos
Main Authors: Ferlin, Alberto, Pepe, Anastasia, Gianesello, Lisa, Garolla, Andrea, Feng, Shu, Giannini, Sandro, Zaccolo, Manuela, Facciolli, Arianna, Morello, Roy, Agoulnik, Alexander I, Foresta, Carlo
Formato: Artigo
Idioma:English
Publicado em: Amer Soc Bone & Mineral Res. 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674542/
https://ncbi.nlm.nih.gov/pubmed/18433302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.080204
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