Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow

X-box binding protein 1 (XBP1) is a key signal transducer in endoplasmic reticulum stress response, and its potential role in the atherosclerosis development is unknown. This study aims to explore the impact of XBP1 on maintaining endothelial integrity related to atherosclerosis and to delineate the...

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Detalhes bibliográficos
Main Authors: Zeng, Lingfang, Zampetaki, Anna, Margariti, Andriana, Pepe, Anna Elena, Alam, Saydul, Martin, Daniel, Xiao, Qingzhong, Wang, Wen, Jin, Zheng-Gen, Cockerill, Gillian, Mori, Kazutoshi, Li, Yi-shuan Julie, Hu, Yanhua, Chien, Shu, Xu, Qingbo
Formato: Artigo
Idioma:English
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676169/
https://ncbi.nlm.nih.gov/pubmed/19416856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903197106
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC2676169/
https://ncbi.nlm.nih.gov/pubmed/19416856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903197106

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