Direct muscle delivery of GDNF with human mesenchymal stem cells improves motor neuron survival and function in a rat model of familial ALS

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease in which there is a progressive loss of motor neurons and their connections to muscle leading to paralysis. To maintain muscle connections in a rat model of familial ALS, we performed intramuscular transplantation with human me...

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Detalhes bibliográficos
Main Authors: Suzuki, Masatoshi, McHugh, Jacalyn, Tork, Craig, Shelley, Brandon, Hayes, Antonio, Bellantuono, Ilaria, Aebischer, Patrick, Svendsen, Clive N.
Formato: Artigo
Idioma:English
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678899/
https://ncbi.nlm.nih.gov/pubmed/18797452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.197
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2678899/
https://ncbi.nlm.nih.gov/pubmed/18797452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.197

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