Prediction of paclitaxel sensitivity by CDK1 and CDK2 activity in human breast cancer cells

INTRODUCTION: Paclitaxel is used widely in the treatment of breast cancer. Not all tumors respond to this drug, however, and the characteristics that distinguish resistant tumors from sensitive tumors are not well defined. Activation of the spindle assembly checkpoint is required for paclitaxel-indu...

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Detalhes bibliográficos
Main Authors: Nakayama, Satoshi, Torikoshi, Yasuhiro, Takahashi, Takeshi, Yoshida, Tomokazu, Sudo, Tamotsu, Matsushima, Tomoko, Kawasaki, Yuko, Katayama, Aya, Gohda, Keigo, Hortobagyi, Gabriel N, Noguchi, Shinzaburo, Sakai, Toshiyuki, Ishihara, Hideki, Ueno, Naoto T
Formato: Artigo
Idioma:English
Publicado em: BioMed Central 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687717/
https://ncbi.nlm.nih.gov/pubmed/19239702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2231
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2687717/
https://ncbi.nlm.nih.gov/pubmed/19239702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2231

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