Enhanced pressor response to increased CSF sodium concentration and to central ANG I in heterozygous α(2) Na(+)-K(+)-ATPase knockout mice

Intracerebroventricular (ICV) infusion of NaCl mimics the effects of a high-salt diet in salt-sensitive hypertension, raising the sodium concentration in the cerebrospinal fluid (CSF [Na]) and subsequently increasing the concentration of an endogenous ouabain-like substance (OLS) in the brain. The O...

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Hauptverfasser: Hou, Xiaohong, Theriault, Steven F., Dostanic-Larson, Iva, Moseley, Amy E., Lingrel, Jerry B, Wu, Hengwei, Dean, Stephanie, Van Huysse, James W.
Format: Artikel
Sprache:English
Veröffentlicht: American Physiological Society 2009
Schlagworte:
Neurohumoral Control of Cardiovascular Function
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689841/
https://ncbi.nlm.nih.gov/pubmed/19244589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00809.2007
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2689841/
https://ncbi.nlm.nih.gov/pubmed/19244589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00809.2007

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