Oxidative stress plays a critical role in inactivating mutant BRAF by geldanamycin derivatives

The geldanamycin derivatives 17-allylamino-17-demethoxygeldanamycin (17-AAG) and 17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG) are promising chemotherapeutic drugs that inhibit heat shock protein 90 (HSP90) function. Previous studies have shown that 17-AAG/DMAG treatment induces the...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fukuyo, Yayoi, Inoue, Masahiro, Nakajima, Takuma, Higashikubo, Ryuji, Horikoshi, Nobuko T, Hunt, Clayton, Usheva, Anny, Freeman, Michael L., Horikoshi, Nobuo
Formatua: Artikulua
Hizkuntza:English
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693332/
https://ncbi.nlm.nih.gov/pubmed/18676857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6602
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC2693332/
https://ncbi.nlm.nih.gov/pubmed/18676857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6602

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