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A quantitative model of transcription factor–activated gene expression
A challenge facing biology is to develop quantitative, predictive models of gene regulation. Eukaryotic promoters contain transcription factor binding sites of differing affinity and accessibility, but we understand little about how these variables combine to generate a fine-tuned, quantitative tran...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2696132/ https://ncbi.nlm.nih.gov/pubmed/18849996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1500 |
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