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3′,4′-Dihydroxyflavonol down-regulates monocyte chemoattractant protein-1 in smooth muscle: role of focal adhesion kinase and PDGF receptor signalling

BACKGROUND AND PURPOSE: We investigated the effects of a synthetic flavonol, 3′,4′-dihydroxyflavonol (DiOHF) on the expression of monocyte chemoattractant protein-1 (MCP-1) in rat vascular smooth muscle cells. EXPERIMENTAL APPROACH: MCP-1 expression was assessed by quantitative real-time PCR and pro...

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Detalhes bibliográficos
Main Authors: Jiang, F, Guo, N, Dusting, GJ
Formato: Artigo
Idioma:English
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707972/
https://ncbi.nlm.nih.gov/pubmed/19371329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00199.x
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