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Foxl2 functions in sex determination and histogenesis throughout mouse ovary development

BACKGROUND: Partial loss of function of the transcription factor FOXL2 leads to premature ovarian failure in women. In animal models, Foxl2 is required for maintenance, and possibly induction, of female sex determination independently of other critical genes, e.g., Rspo1. Here we report expression p...

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Hlavní autoři: Garcia-Ortiz, José Elias, Pelosi, Emanuele, Omari, Shakib, Nedorezov, Timur, Piao, Yulan, Karmazin, Jesse, Uda, Manuela, Cao, Antonio, Cole, Steve W, Forabosco, Antonino, Schlessinger, David, Ottolenghi, Chris
Médium: Článek
Jazyk:English
Vydáno: BioMed Central 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711087/
https://ncbi.nlm.nih.gov/pubmed/19538736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-9-36
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