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Simultaneous Measurements of Solvent Dynamics and Functional Kinetics in a Light-Activated Enzyme

Solvent fluctuations play a key role in controlling protein motions and biological function. Here, we have studied how individual steps of the reaction catalyzed by the light-activated enzyme protochlorophyllide oxidoreductase (POR) couple with solvent dynamics. To simultaneously monitor the catalyt...

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Detalhes bibliográficos
Main Authors: Durin, Guillaume, Delaunay, Aude, Darnault, Claudine, Heyes, Derren J., Royant, Antoine, Vernede, Xavier, Hunter, C. Neil, Weik, Martin, Bourgeois, Dominique
Formato: Artigo
Idioma:English
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717306/
https://ncbi.nlm.nih.gov/pubmed/19254549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.10.065
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