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Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

Some breast cancers have been shown to contain a small fraction of cells characterized by CD44(+)/CD24(−/low) cell-surface antigen profile that have high tumor-initiating potential. In addition, breast cancer cells propagated in vitro as mammospheres (MSs) have also been shown to be enriched for cel...

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Detalhes bibliográficos
Main Authors: Creighton, Chad J., Li, Xiaoxian, Landis, Melissa, Dixon, J. Michael, Neumeister, Veronique M., Sjolund, Ashley, Rimm, David L., Wong, Helen, Rodriguez, Angel, Herschkowitz, Jason I., Fan, Cheng, Zhang, Xiaomei, He, Xiaping, Pavlick, Anne, Gutierrez, M. Carolina, Renshaw, Lorna, Larionov, Alexey A., Faratian, Dana, Hilsenbeck, Susan G., Perou, Charles M., Lewis, Michael T., Rosen, Jeffrey M., Chang, Jenny C.
Formato: Artigo
Idioma:English
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720409/
https://ncbi.nlm.nih.gov/pubmed/19666588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905718106
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