Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers

Aberrant glycosylation is a pathological alteration that is widespread in colon cancer, and usually accompanies the onset and progression of the disease. To date, the molecular mechanisms underlying aberrant glycosylation remain largely unknown. In this study, we identify somatic and germ-line mutat...

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Detalhes bibliográficos
Main Authors: Guda, Kishore, Moinova, Helen, He, Jian, Jamison, Oliver, Ravi, Lakshmeswari, Natale, Leanna, Lutterbaugh, James, Lawrence, Earl, Lewis, Susan, Willson, James K. V., Lowe, John B., Wiesner, Georgia L., Parmigiani, Giovanni, Barnholtz-Sloan, Jill, Dawson, Dawn W., Velculescu, Victor E., Kinzler, Kenneth W., Papadopoulos, Nikolas, Vogelstein, Bert, Willis, Joseph, Gerken, Thomas A., Markowitz, Sanford D.
Formato: Artigo
Idioma:English
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722285/
https://ncbi.nlm.nih.gov/pubmed/19617566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901454106
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2722285/
https://ncbi.nlm.nih.gov/pubmed/19617566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901454106

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