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Depletion of γδ(+) T cells increases CD4(+) FoxP3 (T regulatory) cell response in coxsackievirus B3-induced myocarditis
Coxsackievirus B3 (CVB3) causes severe myocarditis in BALB/c mice which depends upon CD4(+) T helper type 1 [Th1; i.e. interferon-γ(+) (IFN-γ(+))] and γδ(+) cells. Depleting γδ(+) cells using anti-γδ antibody suppresses myocarditis and CD4(+) IFN-γ(+) cell numbers in the spleen and heart of infected...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
Blackwell Science Inc
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2729534/ https://ncbi.nlm.nih.gov/pubmed/19604307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.03034.x |
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