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Restoration of PTEN Expression Alters the Sensitivity of Prostate Cancer Cells to EGFR Inhibitors
INTRODUCTION: Prostate cancer (CaP) progression from an androgen-dependent to an androgen-independent state is associated with overexpression of EGFR family members or activation of their downstream signaling pathways, such as PI3K-Akt and MAPK. Although there are data implicating PI3K-Akt or MAPK p...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2748221/ https://ncbi.nlm.nih.gov/pubmed/18386291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.20745 |
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