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HAT–HDAC interplay modulates global histone H3K14 acetylation in gene-coding regions during stress

Histone acetylation and deacetylation are important for gene regulation. The histone acetyltransferase, Gcn5, is an activator of transcriptional initiation that is recruited to gene promoters. Here, we map genome-wide Gcn5 occupancy and histone H3K14ac at high resolution. Gcn5 is predominantly local...

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Detalhes bibliográficos
Main Authors: Johnsson, Anna, Durand-Dubief, Mickaël, Xue-Franzén, Yongtao, Rönnerblad, Michelle, Ekwall, Karl, Wright, Anthony
Formato: Artigo
Idioma:English
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750064/
https://ncbi.nlm.nih.gov/pubmed/19633696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.127
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