Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4(+) hemangiocytes

The mechanisms through which hematopoietic cytokines accelerate revascularization are unknown. Here, we show that the magnitude of cytokine-mediated release of SDF-1 from platelets and the recruitment of nonendothelial CXCR4(+)VEGFR1(+) hematopoietic progenitors, ‘hemangiocytes,’ constitute the majo...

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Detalhes bibliográficos
Main Authors: Jin, David K, Shido, Koji, Kopp, Hans-Georg, Petit, Isabelle, Shmelkov, Sergey V, Young, Lauren M, Hooper, Andrea T, Amano, Hideki, Avecilla, Scott T, Heissig, Beate, Hattori, Koichi, Zhang, Fan, Hicklin, Daniel J, Wu, Yan, Zhu, Zhenping, Dunn, Ashley, Salari, Hassan, Werb, Zena, Hackett, Neil R, Crystal, Ronald G, Lyden, David, Rafii, Shahin
Formato: Artigo
Idioma:English
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754288/
https://ncbi.nlm.nih.gov/pubmed/16648859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1400
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2754288/
https://ncbi.nlm.nih.gov/pubmed/16648859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1400

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