Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells

Yeast and human Eme1 protein, in complex with Mus81, constitute an endonuclease that cleaves branched DNA structures, especially those arising during stalled DNA replication. We identified mouse Eme1, and show that it interacts with Mus81 to form a complex that preferentially cleaves 3′-flap structu...

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Main Authors: Abraham, Jacinth, Lemmers, Bénédicte, Hande, M.Prakash, Moynahan, Mary Ellen, Chahwan, Charly, Ciccia, Alberto, Essers, Jeroen, Hanada, Katsuhiro, Chahwan, Richard, Khaw, Aik Kia, McPherson, Peter, Shehabeldin, Amro, Laister, Rob, Arrowsmith, Cheryl, Kanaar, Roland, West, Stephen C., Jasin, Maria, Hakem, Razqallah
Formato: Artigo
Idioma:en
Publicado em: Oxford University Press 2003
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC275438/
https://ncbi.nlm.nih.gov/pubmed/14609959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg580
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https://ncbi.nlm.nih.gov/pmc/articles/PMC275438/
https://ncbi.nlm.nih.gov/pubmed/14609959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg580

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