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Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry

We conducted meta-analyses of genome-wide association studies (GWAS) for atrial fibrillation (AF) in participants from five community-based cohorts. Meta-analyses of 896 prevalent (15,768 referents) and 2,517 incident (21,337 referents) AF cases identified a novel locus for AF (ZFHX3, rs2106261, ris...

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Detalhes bibliográficos
Main Authors: Benjamin, Emelia J., Rice, Kenneth M., Arking, Dan E., Pfeufer, Arne, van Noord, Charlotte, Smith, Albert V., Schnabel, Renate B., Bis, Joshua C., Boerwinkle, Eric, Sinner, Moritz F., Dehghan, Abbas, Lubitz, Steven A., D’Agostino, Ralph B., Lumley, Thomas, Ehret, Georg B., Heeringa, Jan, Aspelund, Thor, Newton-Cheh, Christopher, Larson, Martin G., Marciante, Kristin D., Soliman, Elsayed Z., Rivadeneira, Fernando, Wang, Thomas J., Eiriksdottir, Gudny, Levy, Daniel, Psaty, Bruce M., Li, Man, Chamberlain, Alanna M., Hofman, Albert, Vasan, Ramachandran S., Harris, Tamara B., Rotter, Jerome I., Kao, W.H. Linda, Agarwal, Sunil K., Ch. Stricker, Bruno H., Wang, Ke, Launer, Lenore J., Smith, Nicholas L., Chakravarti, Aravinda, Uitterlinden, Andre G., Wolf, Philip A, Sotoodehnia, Nona, Kottgen, Anna, van Duijn, Cornelia M., Lunetta, Kathryn L., Heckbert, Susan R., Gudnason, Vilmundur, Alonso, Alvaro, Kaab, Stefan, Ellinor, Patrick T., Witteman, Jacqueline C.
Formato: Artigo
Idioma:English
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761746/
https://ncbi.nlm.nih.gov/pubmed/19597492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.416
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