APT102, a Novel ADPase, Cooperates With Aspirin to Disrupt Bone Metastasis in Mice

Platelets contribute to the development of metastasis, the most common cause of mortality in cancer patients, but the precise role that anti-platelet drugs play in cancer treatment is not defined. Metastatic tumor cells can produce platelet aIIbb3 activators, such as ADP and thromboxane A(2) (TXA(2)...

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Hauptverfasser: Uluçkan, Özge, Eagleton, Mark C., Floyd, Desiree H., Morgan, Elizabeth A., Hirbe, Angela C., Kramer, Matthew, Dowland, Nikki, Prior, Julie L., Piwnica-Worms, David, Jeong, Soon Seog, Chen, Ridong, Weilbaecher, Katherine
Format: Artikel
Sprache:English
Veröffentlicht: 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763643/
https://ncbi.nlm.nih.gov/pubmed/18260128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21709
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https://ncbi.nlm.nih.gov/pmc/articles/PMC2763643/
https://ncbi.nlm.nih.gov/pubmed/18260128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21709

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