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Species-barrier-independent prion replication in apparently resistant species

Transmission of prions between mammalian species is thought to be limited by a “species barrier,” which depends on differences in the primary structure of prion proteins in the infecting inoculum and the host. Here we demonstrate that a strain of hamster prions thought to be nonpathogenic for conven...

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Detalhes bibliográficos
Main Authors: Hill, Andrew F., Joiner, Susan, Linehan, Jackie, Desbruslais, Melanie, Lantos, Peter L., Collinge, John
Formato: Artigo
Idioma:en
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC27848/
https://ncbi.nlm.nih.gov/pubmed/10963685
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