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Nonsense mutations in the human beta-globin gene affect mRNA metabolism.

A number of premature translation termination mutations (nonsense mutations) have been described in the human alpha- and beta-globin genes. Studies on mRNA isolated from patients with beta zero-thalassemia have shown that for both the beta-17 and the beta-39 mutations less than normal levels of beta...

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Detalhes bibliográficos
Main Authors:	Baserga, S J, Benz, E J, Eva, A, Vecchio, G, Rao, C D, Tronick, S R, Aaronson, S A, Harrington, M A, Jones, P A, Imagawa, M, Karin, M, Rosen, C A, Terwilliger, E, Dayton, A, Sodroski, J G, Haseltine, W A, Bae, Y S, Kawasaki, I, Ikeda, H, Liu, L F, Kozasa, T, Itoh, H, Tsukamoto, T, Kaziro, Y, Simmons, D T, Nagley, P, Farrell, L B, Gearing, D P, Nero, D, Meltzer, S, Devenish, R J, Cherbas, P, Cherbas, L, Lee, S S, Nakanishi, K, Jazwinski, S M, Weichselbaum, R R, Beckett, M, Diamond, A, Borner, C, Eppenberger, U, Wyss, R, Fabbro, D, Fitzpatrick, L A, Chin, H, Nirenberg, M, Aurbach, G D, Diffley, J F, Stillman, B, Ruffner, D E, Dugaiczyk, A, Celenza, J L, Marshall-Carlson, L, Carlson, M, Lopez, J A, Chung, D W, Fujikawa, K, Hagen, F S, Davie, E W, Roth, G J, Amit, D J, Heyn, M. P., Westerhausen, J., Wallat, I., Seiff, F., Murray, L P, Hofrichter, J, Henry, E R, Ikeda-Saito, M, Kitagishi, K, Yonetani, T, Eaton, W A, Fodor, S P, Pollard, W T, Gebhard, R, van den Berg, E M, Lugtenburg, J, Mathies, R A, Ben-Ze'ev, A, Robinson, G S, Bucher, N L, Farmer, S R, Gaudino, G, Cirillo, D, Naldini, L, Rossino, P, Comoglio, P M, Leibold, E A, Munro, H N, Paules, R S, Cordeiro-Stone, M, Mass, M J, Poirier, M C, Yuspa, S H, Kaufman, D G, Meier, K, Klein, C, Jones, F S, Burgoon, M P, Hoffman, S, Crossin, K L, Cunningham, B A, Edelman, G M, Sorrentino, V, McKinney, M D, Giorgi, M, Geremia, R, Fleissner, E, Martin, Thomas E., Brabant, M, McConlogue, L, van Daalen Wetters, T, Coffino, P, Wu, M, Allis, C D, Gorovsky, M A, Bookstein, R, Lee, E Y, To, H, Young, L J, Sery, T W, Hayes, R C, Friedmann, T, Lee, W H, Haluska, F G, Huebner, K, Isobe, M, Nishimura, T, Croce, C M, Vogt, P K, Heidmann, T, Heidmann, O, Nicolas, J F, Makris, J C, Nordmann, P L, Reznikoff, W S, Latron, F, Jotterand-Bellomo, M, Maffei, A, Scarpellino, L, Bernard, M, Strominger, J L, Accolla, R S, Himeno, K, Good, R A, Hibbs, M L, Bonadonna, L, Scott, B M, McKenzie, I F, Hogarth, P M, Schwager, J, Mikoryak, C A, Steiner, L A, Haas, I G, Meo, T, Reiser, H, Coligan, J, Palmer, E, Benacerraf, B, Rock, K L, Mendlovic, S, Brocke, S, Shoenfeld, Y, Ben-Bassat, M, Meshorer, A, Bakimer, R, Mozes, E, Jamieson, B D, Ahmed, R, Arnold, B, Dill, O, Küblbeck, G, Jatsch, L, Simon, M M, Tucker, J, Hämmerling, G J, De Plaen, E, Lurquin, C, Van Pel, A, Mariamé, B, Szikora, J P, Wölfel, T, Sibille, C, Chomez, P, Boon, T, Hornbeck, P, Huang, K P, Paul, W E, Stevens, R L, Fox, C C, Lichtenstein, L M, Austen, K F, Saito, H, Hatake, K, Dvorak, A M, Leiferman, K M, Donnenberg, A D, Arai, N, Ishizaka, K, Ishizaka, T
Formato:	Artigo
Idioma:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
Publicado em:	1988
Assuntos:	Research Article Correction Biological Sciences: Biophysics Biological Sciences: Ecology
Acesso em linha:	https://ncbi.nlm.nih.gov/pmc/articles/PMC279927/ https://ncbi.nlm.nih.gov/pubmed/3353367 https://ncbi.nlm.nih.gov/pmc/articles/PMC279928/ https://ncbi.nlm.nih.gov/pubmed/3281159 https://ncbi.nlm.nih.gov/pmc/articles/PMC279929/ https://ncbi.nlm.nih.gov/pubmed/3281160 https://ncbi.nlm.nih.gov/pmc/articles/PMC279930/ https://ncbi.nlm.nih.gov/pubmed/2832844 https://ncbi.nlm.nih.gov/pmc/articles/PMC279931/ https://ncbi.nlm.nih.gov/pubmed/2832845 https://ncbi.nlm.nih.gov/pmc/articles/PMC279932/ https://ncbi.nlm.nih.gov/pubmed/3127824 https://ncbi.nlm.nih.gov/pmc/articles/PMC279933/ https://ncbi.nlm.nih.gov/pubmed/2832846 https://ncbi.nlm.nih.gov/pmc/articles/PMC279934/ https://ncbi.nlm.nih.gov/pubmed/2895470 https://ncbi.nlm.nih.gov/pmc/articles/PMC279935/ https://ncbi.nlm.nih.gov/pubmed/3127825 https://ncbi.nlm.nih.gov/pmc/articles/PMC279936/ https://ncbi.nlm.nih.gov/pubmed/3281161 https://ncbi.nlm.nih.gov/pmc/articles/PMC279937/ https://ncbi.nlm.nih.gov/pubmed/3162593 https://ncbi.nlm.nih.gov/pmc/articles/PMC279938/ https://ncbi.nlm.nih.gov/pubmed/3353368 https://ncbi.nlm.nih.gov/pmc/articles/PMC279939/ https://ncbi.nlm.nih.gov/pubmed/2451241 https://ncbi.nlm.nih.gov/pmc/articles/PMC279940/ https://ncbi.nlm.nih.gov/pubmed/3281162 https://ncbi.nlm.nih.gov/pmc/articles/PMC279941/ https://ncbi.nlm.nih.gov/pubmed/3353369 https://ncbi.nlm.nih.gov/pmc/articles/PMC279942/ https://ncbi.nlm.nih.gov/pubmed/3281163 https://ncbi.nlm.nih.gov/pmc/articles/PMC279943/ https://ncbi.nlm.nih.gov/pubmed/3353370 https://ncbi.nlm.nih.gov/pmc/articles/PMC279944/ https://ncbi.nlm.nih.gov/pmc/articles/PMC279945/ https://ncbi.nlm.nih.gov/pubmed/3353371 https://ncbi.nlm.nih.gov/pmc/articles/PMC279946/ https://ncbi.nlm.nih.gov/pubmed/16593918 https://ncbi.nlm.nih.gov/pmc/articles/PMC279947/ https://ncbi.nlm.nih.gov/pubmed/3353372 https://ncbi.nlm.nih.gov/pmc/articles/PMC279948/ https://ncbi.nlm.nih.gov/pubmed/3353373 https://ncbi.nlm.nih.gov/pmc/articles/PMC279949/ https://ncbi.nlm.nih.gov/pubmed/3353374 https://ncbi.nlm.nih.gov/pmc/articles/PMC279950/ https://ncbi.nlm.nih.gov/pubmed/2451242 https://ncbi.nlm.nih.gov/pmc/articles/PMC279951/ https://ncbi.nlm.nih.gov/pubmed/3127826 https://ncbi.nlm.nih.gov/pmc/articles/PMC279952/ https://ncbi.nlm.nih.gov/pubmed/3127827 https://ncbi.nlm.nih.gov/pmc/articles/PMC279953/ https://ncbi.nlm.nih.gov/pubmed/2832847 https://ncbi.nlm.nih.gov/pmc/articles/PMC279954/ https://ncbi.nlm.nih.gov/pubmed/2451243 https://ncbi.nlm.nih.gov/pmc/articles/PMC279955/ https://ncbi.nlm.nih.gov/pubmed/2965388 https://ncbi.nlm.nih.gov/pmc/articles/PMC279956/ https://ncbi.nlm.nih.gov/pubmed/16593919 https://ncbi.nlm.nih.gov/pmc/articles/PMC279957/ https://ncbi.nlm.nih.gov/pubmed/3353375 https://ncbi.nlm.nih.gov/pmc/articles/PMC279958/ https://ncbi.nlm.nih.gov/pubmed/3353376 https://ncbi.nlm.nih.gov/pmc/articles/PMC279959/ https://ncbi.nlm.nih.gov/pubmed/2895471 https://ncbi.nlm.nih.gov/pmc/articles/PMC279960/ https://ncbi.nlm.nih.gov/pubmed/3127828 https://ncbi.nlm.nih.gov/pmc/articles/PMC279961/ https://ncbi.nlm.nih.gov/pubmed/2832848 https://ncbi.nlm.nih.gov/pmc/articles/PMC279962/ https://ncbi.nlm.nih.gov/pubmed/2832849 https://ncbi.nlm.nih.gov/pmc/articles/PMC279963/ https://ncbi.nlm.nih.gov/pubmed/3127829 https://ncbi.nlm.nih.gov/pmc/articles/PMC279964/ https://ncbi.nlm.nih.gov/pmc/articles/PMC279965/ https://ncbi.nlm.nih.gov/pubmed/3281164 https://ncbi.nlm.nih.gov/pmc/articles/PMC279966/ https://ncbi.nlm.nih.gov/pubmed/2965389 https://ncbi.nlm.nih.gov/pmc/articles/PMC279967/ https://ncbi.nlm.nih.gov/pubmed/2451244 https://ncbi.nlm.nih.gov/pmc/articles/PMC279968/ https://ncbi.nlm.nih.gov/pubmed/2895472 https://ncbi.nlm.nih.gov/pmc/articles/PMC279969/ https://ncbi.nlm.nih.gov/pubmed/2895473 https://ncbi.nlm.nih.gov/pmc/articles/PMC279970/ https://ncbi.nlm.nih.gov/pubmed/3258423 https://ncbi.nlm.nih.gov/pmc/articles/PMC279971/ https://ncbi.nlm.nih.gov/pubmed/3258424 https://ncbi.nlm.nih.gov/pmc/articles/PMC279972/ https://ncbi.nlm.nih.gov/pubmed/2965390 https://ncbi.nlm.nih.gov/pmc/articles/PMC279973/ https://ncbi.nlm.nih.gov/pubmed/3127830 https://ncbi.nlm.nih.gov/pmc/articles/PMC279974/ https://ncbi.nlm.nih.gov/pubmed/3353377 https://ncbi.nlm.nih.gov/pmc/articles/PMC279975/ https://ncbi.nlm.nih.gov/pubmed/3353378 https://ncbi.nlm.nih.gov/pmc/articles/PMC279976/ https://ncbi.nlm.nih.gov/pubmed/3258425
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Nonsense mutations in the human beta-globin gene affect mRNA metabolism.

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