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Evaluation of the phosphodiesterase 3 inhibitor ORG 9935 as a contraceptive in female macaques: Initial trials
BACKGROUND: The study was conducted to determine whether a phosphodiesterase (PDE) 3 inhibitor has potential as a novel contraceptive in primates. METHODS: Regularly cycling adult female cynomolgus macaques of proven fertility (n=16) were treated for 7 months with placebo (controls) or the PDE 3 inh...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2813210/ https://ncbi.nlm.nih.gov/pubmed/20103457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.contraception.2009.09.015 |
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