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Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5′ olfactory receptor gene cluster
In a genome-wide association study of 848 blacks with sickle cell anemia, we identified single nucleotide polymorphisms (SNPs) associated with fetal hemoglobin concentration. The most significant SNPs in a discovery sample were tested in a replication set of 305 blacks with sickle cell anemia and in...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
American Society of Hematology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832816/ https://ncbi.nlm.nih.gov/pubmed/20018918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-239517 |
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