A pilot study of high-throughput, sequence-based mutational profiling of primary human acute myeloid leukemia cell genomes

In this pilot study, we used primary human acute myeloid leukemia (AML) cell genomes as templates for exonic PCR amplification, followed by high-throughput resequencing, analyzing ≈7 million base pairs of DNA from 140 AML samples and 48 controls. We identified six previously described, and seven pre...

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Detalhes bibliográficos
Main Authors: Ley, Timothy J., Minx, Patrick J., Walter, Matthew J., Ries, Rhonda E., Sun, Hui, McLellan, Michael, DiPersio, John F., Link, Daniel C., Tomasson, Michael H., Graubert, Timothy A., McLeod, Howard, Khoury, Hanna, Watson, Mark, Shannon, William, Trinkaus, Kathryn, Heath, Sharon, Vardiman, James W., Caligiuri, Michael A., Bloomfield, Clara D., Milbrandt, Jeffrey D., Mardis, Elaine R., Wilson, Richard K.
Formato: Artigo
Idioma:en
Publicado em: National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC283582/
https://ncbi.nlm.nih.gov/pubmed/14614138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2335924100
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC283582/
https://ncbi.nlm.nih.gov/pubmed/14614138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2335924100

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