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Penetration of beta-lactam antibiotics into their target enzymes in Pseudomonas aeruginosa: comparison of a highly sensitive mutant with its parent strain.

Pseudomonas aeruginosa K 799/WT and a mutant of this strain, P. aeruginosa K 799/61 ("mutant 61"), that is very sensitive to most beta-lactam antibiotics tested were used to assess the importance of penetration barriers in the resistance of P. aeruginosa to penicillins and cephalosporins....

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Main Authors:	Zimmermann, W, Ralph, E D, Amatnieks, Y E, Yasuda, K, Kurashige, S, Mitsuhashi, S, Döbeli, H, Nüesch, J, Vanhoof, R, Gordts, B, Dierickx, R, Coignau, H, Butzler, J P, Yogev, R, Kabat, W J, Koff, W C, Elm, J L, Halstead, S B, Giard, D J, Fleischaker, R J, Bolton, L, Foleno, B, Means, B, Petrucelli, S, Soike, K F, Felsenfeld, A D, Gibson, S, Gerone, P J, Georgopapadakou, N H, Liu, F Y, Dick, J D, Merz, W G, Saral, R, Brook, I, Calhoun, L, Yocum, P, Simon, G L, Snydman, D R, Tally, F P, Gorbach, S L, Speedie, M K, Fique, D V, Blomster, R N, Hottendorf, G H, Gordon, L L, White, A R, Comber, K R, Sutherland, R, Restrepo, A, Arango, M D, Matsubara, N, Minami, S, Matsuhashi, M, Takaoka, M, Jørgensen, S T, Oliva, B, Grinsted, J, Bennett, P M, Meisel, S, Pupkoff, R, Svaan, J, Pesanti, E L, Cherne, J E, Peterson, L R, Aronoff, G R, Szwed, J J, Nelson, R L, Marcus, E L, Kleit, S A, Mendoza, C, Garcia, J M, Llaneza, J, Mendez, F J, Hardisson, C, Ortiz, J M, Olsson-Liljequist, B, Dornbusch, K, Nord, C E, Akiyama, S, Tabuki, T, Kaneko, M, Komiyama, S, Kuwano, M, Anné, J, De Clercq, E, Eyssen, H, Dann, O, Seddon, M, Wise, R, Gillett, A P, Livingston, R, Agee, C C, Engelhardt, J A, Gabridge, M G, Smit, H, van der Goot, H, Nauta, W T, Pijper, P J, Balt, S, de Bolster, M W, Stouthamer, A H, Verheul, H, Vis, R D, Iwahi, T, Tsuchiya, K, Thompson, S G, Burd, J F, Mehl, J K, Witiak, D T, Hamparian, V V, Hughes, J H, Kim, K S, Sapienza, V J, Carp, R I, Lysko, P G, Morse, S A, Ruebush, T K, Contacos, P G, Steck, E A, Shannon, K, King, A, Warren, C, Phillips, I, Wade, J C, Schimpff, S C, Newman, K A, Fortner, C L, Moody, M R, Young, V M, Wiernik, P H, Tight, R R, Neu, H C, Fu, K P, Casero, R A, Klayman, D L, Childs, G E, Scovill, J P, Desjardins, R E, Harvey, R J, Koch, A L, Thornsberry, C, Barry, A L, Jones, R N, Baker, C N, Badal, R E, Packer, R R, Parker, R A, Gilbert, D N, Houghton, D C, Porter, G A, Bennett, W M, Svedhem, A, Alestig, K, Jertborn, M, Pohlod, D J, Saravolatz, L D, Quinn, E L, Somerville, M M, Yoshikawa, T T, Shibata, S A, Herbert, P, Oill, P A, David, H L, Clavel, S, Clement, F, Moniz-Pereira, J, Crum, J W, Duangmani, C, Vibulyasekha, S, Suthisomboon, K
Formato:	Artigo
Idioma:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
Publicado em:	1980
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.gov/pmc/articles/PMC283945/ https://ncbi.nlm.nih.gov/pubmed/6774666 https://ncbi.nlm.nih.gov/pmc/articles/PMC283946/ https://ncbi.nlm.nih.gov/pubmed/6968175 https://ncbi.nlm.nih.gov/pmc/articles/PMC283947/ https://ncbi.nlm.nih.gov/pubmed/6998373 https://ncbi.nlm.nih.gov/pmc/articles/PMC283948/ https://ncbi.nlm.nih.gov/pubmed/7191238 https://ncbi.nlm.nih.gov/pmc/articles/PMC283949/ https://ncbi.nlm.nih.gov/pubmed/7416738 https://ncbi.nlm.nih.gov/pmc/articles/PMC283950/ https://ncbi.nlm.nih.gov/pubmed/6968176 https://ncbi.nlm.nih.gov/pmc/articles/PMC283951/ https://ncbi.nlm.nih.gov/pubmed/7416739 https://ncbi.nlm.nih.gov/pmc/articles/PMC283952/ https://ncbi.nlm.nih.gov/pubmed/6158290 https://ncbi.nlm.nih.gov/pmc/articles/PMC283953/ https://ncbi.nlm.nih.gov/pubmed/7416740 https://ncbi.nlm.nih.gov/pmc/articles/PMC283954/ https://ncbi.nlm.nih.gov/pubmed/6158291 https://ncbi.nlm.nih.gov/pmc/articles/PMC283955/ https://ncbi.nlm.nih.gov/pubmed/7416741 https://ncbi.nlm.nih.gov/pmc/articles/PMC283956/ https://ncbi.nlm.nih.gov/pubmed/7416742 https://ncbi.nlm.nih.gov/pmc/articles/PMC283957/ https://ncbi.nlm.nih.gov/pubmed/6968177 https://ncbi.nlm.nih.gov/pmc/articles/PMC283958/ https://ncbi.nlm.nih.gov/pubmed/6448020 https://ncbi.nlm.nih.gov/pmc/articles/PMC283959/ https://ncbi.nlm.nih.gov/pubmed/6998375 https://ncbi.nlm.nih.gov/pmc/articles/PMC283960/ https://ncbi.nlm.nih.gov/pubmed/7416743 https://ncbi.nlm.nih.gov/pmc/articles/PMC283961/ https://ncbi.nlm.nih.gov/pubmed/6774663 https://ncbi.nlm.nih.gov/pmc/articles/PMC283962/ https://ncbi.nlm.nih.gov/pubmed/7416744 https://ncbi.nlm.nih.gov/pmc/articles/PMC283963/ https://ncbi.nlm.nih.gov/pubmed/6448021 https://ncbi.nlm.nih.gov/pmc/articles/PMC283964/ https://ncbi.nlm.nih.gov/pubmed/6998376 https://ncbi.nlm.nih.gov/pmc/articles/PMC283965/ https://ncbi.nlm.nih.gov/pubmed/7416745 https://ncbi.nlm.nih.gov/pmc/articles/PMC283966/ https://ncbi.nlm.nih.gov/pubmed/7416746 https://ncbi.nlm.nih.gov/pmc/articles/PMC283967/ https://ncbi.nlm.nih.gov/pubmed/6774664 https://ncbi.nlm.nih.gov/pmc/articles/PMC283968/ https://ncbi.nlm.nih.gov/pubmed/7416747 https://ncbi.nlm.nih.gov/pmc/articles/PMC283973/ https://ncbi.nlm.nih.gov/pubmed/7004337 https://ncbi.nlm.nih.gov/pmc/articles/PMC283974/ https://ncbi.nlm.nih.gov/pubmed/6969573 https://ncbi.nlm.nih.gov/pmc/articles/PMC283975/ https://ncbi.nlm.nih.gov/pubmed/6160808 https://ncbi.nlm.nih.gov/pmc/articles/PMC283976/ https://ncbi.nlm.nih.gov/pubmed/7447403 https://ncbi.nlm.nih.gov/pmc/articles/PMC283977/ https://ncbi.nlm.nih.gov/pubmed/7447404 https://ncbi.nlm.nih.gov/pmc/articles/PMC283978/ https://ncbi.nlm.nih.gov/pubmed/6778378 https://ncbi.nlm.nih.gov/pmc/articles/PMC283979/ https://ncbi.nlm.nih.gov/pubmed/6778379 https://ncbi.nlm.nih.gov/pmc/articles/PMC283980/ https://ncbi.nlm.nih.gov/pubmed/7004338 https://ncbi.nlm.nih.gov/pmc/articles/PMC283981/ https://ncbi.nlm.nih.gov/pubmed/7004339 https://ncbi.nlm.nih.gov/pmc/articles/PMC283982/ https://ncbi.nlm.nih.gov/pubmed/6255860 https://ncbi.nlm.nih.gov/pmc/articles/PMC283983/ https://ncbi.nlm.nih.gov/pubmed/7447405 https://ncbi.nlm.nih.gov/pmc/articles/PMC283984/ https://ncbi.nlm.nih.gov/pubmed/6778380 https://ncbi.nlm.nih.gov/pmc/articles/PMC283985/ https://ncbi.nlm.nih.gov/pubmed/7447406 https://ncbi.nlm.nih.gov/pmc/articles/PMC283986/ https://ncbi.nlm.nih.gov/pubmed/6969574 https://ncbi.nlm.nih.gov/pmc/articles/PMC283987/ https://ncbi.nlm.nih.gov/pubmed/6449902 https://ncbi.nlm.nih.gov/pmc/articles/PMC283988/ https://ncbi.nlm.nih.gov/pubmed/7447407 https://ncbi.nlm.nih.gov/pmc/articles/PMC283989/ https://ncbi.nlm.nih.gov/pubmed/7447408 https://ncbi.nlm.nih.gov/pmc/articles/PMC283990/ https://ncbi.nlm.nih.gov/pubmed/7447409 https://ncbi.nlm.nih.gov/pmc/articles/PMC283991/ https://ncbi.nlm.nih.gov/pubmed/6160809 https://ncbi.nlm.nih.gov/pmc/articles/PMC283992/ https://ncbi.nlm.nih.gov/pubmed/7447410 https://ncbi.nlm.nih.gov/pmc/articles/PMC283993/ https://ncbi.nlm.nih.gov/pubmed/7447411 https://ncbi.nlm.nih.gov/pmc/articles/PMC283994/ https://ncbi.nlm.nih.gov/pubmed/7447412 https://ncbi.nlm.nih.gov/pmc/articles/PMC283995/ https://ncbi.nlm.nih.gov/pubmed/6969575 https://ncbi.nlm.nih.gov/pmc/articles/PMC283996/ https://ncbi.nlm.nih.gov/pubmed/6778381 https://ncbi.nlm.nih.gov/pmc/articles/PMC283997/ https://ncbi.nlm.nih.gov/pubmed/7447413 https://ncbi.nlm.nih.gov/pmc/articles/PMC283998/ https://ncbi.nlm.nih.gov/pubmed/6778382
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Penetration of beta-lactam antibiotics into their target enzymes in Pseudomonas aeruginosa: comparison of a highly sensitive mutant with its parent strain.

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