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Disruption of LGI1–linked synaptic complex causes abnormal synaptic transmission and epilepsy

Epilepsy is a devastating and poorly understood disease. Mutations in a secreted neuronal protein, leucine-rich glioma inactivated 1 (LGI1), were reported in patients with an inherited form of human epilepsy, autosomal dominant partial epilepsy with auditory features (ADPEAF). Here, we report an ess...

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Detalhes bibliográficos
Formato: Artigo
Idioma:en
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840530/
https://ncbi.nlm.nih.gov/pubmed/20133599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914537107
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