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Genetic alterations in streptomycin-resistant Mycobacterium tuberculosis: mapping of mutations conferring resistance.

We report on the identification of mutations associated with streptomycin resistance in Mycobacterium tuberculosis. Two isolates (3656 and 3976) showed a wild-type ribosomal protein, S12, but exhibited a single point mutation at 16S rRNA position 491 (C-->T) or 512 (C-->T), respectively. Seque...

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Detalhes bibliográficos
Main Authors: Meier, A, Kirschner, P, Bange, F C, Vogel, U, Böttger, E C
Formato: Artigo
Idioma:en
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC284431/
https://ncbi.nlm.nih.gov/pubmed/8192448
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