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Identification of the convulsant opiate thebaine in mammalian brain.

The convulsant opiate thebaine, an intermediate of morphine biosynthesis, was purified from bovine brain to homogeneity by gel filtration and high-performance liquid chromatography (HPLC) monitored by a radioimmunoassay. The immunoreactive material behaved identically to standard thebaine in two HPL...

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Detalhes bibliográficos
Main Authors:	Kodaira, H, Lisek, C A, Jardine, I, Arimura, A, Spector, S, Wible, B A, Smith, K E, Angelides, K J, Castrén, E, Saavedra, J M, Ebner, F F, Erzurumlu, R S, Lee, S M, Stoffers, D A, Green, C B, Eipper, B A, Javitt, D C, Zukin, S R, Tate-Ostroff, B, Majocha, R E, Marotta, C A, Raggenbass, M, Tribollet, E, Dubois-Dauphin, M, Dreifuss, J J, Duesberg, P H, Karle, I L, Flippen-Anderson, J L, Uma, K, Balaram, H, Balaram, P, Krishnamurthy, T, Szafraniec, L, Hunt, D F, Shabanowitz, J, Yates, J R, Hauer, C R, Carmichael, W W, Skulberg, O, Codd, G A, Missler, S, Brini, Andrea, Teolis, Antonio G. B., Lenfant, M, Wdzieczak-Bakala, J, Guittet, E, Prome, J C, Sotty, D, Frindel, E, Leister, K J, Schenerman, M A, Racker, E, Driscoll, J, Goldberg, A L, Riddle, R D, Yamamoto, M, Engel, J D, Knight, K L, Sauer, R T, Rubin, J S, Osada, H, Finch, P W, Taylor, W G, Rudikoff, S, Aaronson, S A, Kräusslich, H G, Ingraham, R H, Skoog, M T, Wimmer, E, Pallai, P V, Carter, C A, Friedman, B A, van Amsterdam, J, Fujiki, H, Rosner, M R, Burk, S C, Papastavros, M Z, McCormick, F, Redfield, A G, Gentz, R, Chen, C H, Rosen, C A, Curnutte, J T, Scott, P J, Mayo, L A, Arnosti, D N, Chamberlin, M J, Coghlan, V M, Vickery, L E, Reid, L E, Brasnett, A H, Gilbert, C S, Porter, A C, Gewert, D R, Stark, G R, Kerr, I M, Gouaux, J E, Lipscomb, W N, Ghosh, B K, Owens, K, Pietri, R, Peterkofsky, A, Colvard, D S, Eriksen, E F, Keeting, P E, Wilson, E M, Lubahn, D B, French, F S, Riggs, B L, Spelsberg, T C, Cobitz, A R, Yim, E H, Brown, W R, Perou, C M, Tamanoi, F, Lannigan, D A, Notides, A C, Molina Y Vedia, L, Lapetina, E G, Braedt, G, Smith, G R, Zaitlin, D, Hu, J, Bogorad, L, Raymond, J A, Wilson, P, DeVries, A L, Reiss, B, Wasmann, C C, Schell, J, Bohnert, H J, Barbier-Brygoo, Helene, Ephritikhine, Genevieve, Klämbt, Dieter, Ghislain, Michel, Guern, Jean, Metraux, J P, Burkhart, W, Moyer, M, Dincher, S, Middlesteadt, W, Williams, S, Payne, G, Carnes, M, Ryals, J, Golden, A, Brugge, J S, Nimpf, J, Radosavljevic, M, Schneider, W J, King, N J, Maxwell, L E, Kesson, A M, Streeten, E A, Ornberg, R, Curcio, F, Sakaguchi, K, Marx, S, Aurbach, G D, Brandi, M L, Habenicht, A J, Goerig, M, Rothe, D E, Specht, E, Ziegler, R, Glomset, J A, Graf, T, Honegger, A M, Kris, R M, Ullrich, A, Schlessinger, J, Satir, B H, Hamasaki, T, Reichman, M, Murtaugh, T J, Yannas, I V, Lee, E, Orgill, D P, Skrabut, E M, Murphy, G F, Robbins, S M, Williams, J G, Jermyn, K A, Spiegelman, G B, Weeks, G, Winkler, C, Schultz, A, Cevario, S, O'Brien, S, Langlois, S, Deeb, S, Brunzell, J D, Kastelein, J J, Hayden, M R, McGuire, M C, Nogueira, C P, Bartels, C F, Lightstone, H, Hajra, A, Van der Spek, A F, Lockridge, O, La Du, B N
Formato:	Artigo
Idioma:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
Publicado em:	1989
Assuntos:	Research Article Physical Sciences: Mathematics Biological Sciences: Botany
Acesso em linha:	https://ncbi.nlm.nih.gov/pmc/articles/PMC286545/ https://ncbi.nlm.nih.gov/pubmed/2911601 https://ncbi.nlm.nih.gov/pmc/articles/PMC286546/ https://ncbi.nlm.nih.gov/pubmed/2536175 https://ncbi.nlm.nih.gov/pmc/articles/PMC286547/ https://ncbi.nlm.nih.gov/pubmed/2911602 https://ncbi.nlm.nih.gov/pmc/articles/PMC286548/ https://ncbi.nlm.nih.gov/pubmed/2911603 https://ncbi.nlm.nih.gov/pmc/articles/PMC286549/ https://ncbi.nlm.nih.gov/pubmed/2911604 https://ncbi.nlm.nih.gov/pmc/articles/PMC286550/ https://ncbi.nlm.nih.gov/pubmed/2536176 https://ncbi.nlm.nih.gov/pmc/articles/PMC286551/ https://ncbi.nlm.nih.gov/pubmed/2563169 https://ncbi.nlm.nih.gov/pmc/articles/PMC286552/ https://ncbi.nlm.nih.gov/pubmed/2536177 https://ncbi.nlm.nih.gov/pmc/articles/PMC286556/ https://ncbi.nlm.nih.gov/pubmed/2644642 https://ncbi.nlm.nih.gov/pmc/articles/PMC286557/ https://ncbi.nlm.nih.gov/pubmed/2915976 https://ncbi.nlm.nih.gov/pmc/articles/PMC286558/ https://ncbi.nlm.nih.gov/pubmed/2492662 https://ncbi.nlm.nih.gov/pmc/articles/PMC286559/ https://ncbi.nlm.nih.gov/pubmed/16594014 https://ncbi.nlm.nih.gov/pmc/articles/PMC286560/ https://ncbi.nlm.nih.gov/pubmed/2915977 https://ncbi.nlm.nih.gov/pmc/articles/PMC286561/ https://ncbi.nlm.nih.gov/pubmed/2536932 https://ncbi.nlm.nih.gov/pmc/articles/PMC286562/ https://ncbi.nlm.nih.gov/pubmed/2536933 https://ncbi.nlm.nih.gov/pmc/articles/PMC286563/ https://ncbi.nlm.nih.gov/pubmed/2915978 https://ncbi.nlm.nih.gov/pmc/articles/PMC286564/ https://ncbi.nlm.nih.gov/pubmed/2644643 https://ncbi.nlm.nih.gov/pmc/articles/PMC286565/ https://ncbi.nlm.nih.gov/pubmed/2915979 https://ncbi.nlm.nih.gov/pmc/articles/PMC286566/ https://ncbi.nlm.nih.gov/pubmed/2644644 https://ncbi.nlm.nih.gov/pmc/articles/PMC286567/ https://ncbi.nlm.nih.gov/pubmed/2492663 https://ncbi.nlm.nih.gov/pmc/articles/PMC286568/ https://ncbi.nlm.nih.gov/pubmed/2644645 https://ncbi.nlm.nih.gov/pmc/articles/PMC286569/ https://ncbi.nlm.nih.gov/pubmed/2536934 https://ncbi.nlm.nih.gov/pmc/articles/PMC286570/ https://ncbi.nlm.nih.gov/pubmed/2915980 https://ncbi.nlm.nih.gov/pmc/articles/PMC286571/ https://ncbi.nlm.nih.gov/pubmed/2644646 https://ncbi.nlm.nih.gov/pmc/articles/PMC286572/ https://ncbi.nlm.nih.gov/pubmed/2644647 https://ncbi.nlm.nih.gov/pmc/articles/PMC286573/ https://ncbi.nlm.nih.gov/pubmed/2492664 https://ncbi.nlm.nih.gov/pmc/articles/PMC286574/ https://ncbi.nlm.nih.gov/pubmed/2644648 https://ncbi.nlm.nih.gov/pmc/articles/PMC286575/ https://ncbi.nlm.nih.gov/pubmed/2644649 https://ncbi.nlm.nih.gov/pmc/articles/PMC286576/ https://ncbi.nlm.nih.gov/pubmed/2915981 https://ncbi.nlm.nih.gov/pmc/articles/PMC286577/ https://ncbi.nlm.nih.gov/pubmed/2492665 https://ncbi.nlm.nih.gov/pmc/articles/PMC286578/ https://ncbi.nlm.nih.gov/pubmed/2915982 https://ncbi.nlm.nih.gov/pmc/articles/PMC286579/ https://ncbi.nlm.nih.gov/pubmed/2464829 https://ncbi.nlm.nih.gov/pmc/articles/PMC286580/ https://ncbi.nlm.nih.gov/pubmed/2536935 https://ncbi.nlm.nih.gov/pmc/articles/PMC286581/ https://ncbi.nlm.nih.gov/pubmed/2644650 https://ncbi.nlm.nih.gov/pmc/articles/PMC286582/ https://ncbi.nlm.nih.gov/pubmed/2915983 https://ncbi.nlm.nih.gov/pmc/articles/PMC286583/ https://ncbi.nlm.nih.gov/pubmed/2915984 https://ncbi.nlm.nih.gov/pmc/articles/PMC286584/ https://ncbi.nlm.nih.gov/pubmed/16594015 https://ncbi.nlm.nih.gov/pmc/articles/PMC286585/ https://ncbi.nlm.nih.gov/pubmed/2915985 https://ncbi.nlm.nih.gov/pmc/articles/PMC286586/ https://ncbi.nlm.nih.gov/pubmed/2464830 https://ncbi.nlm.nih.gov/pmc/articles/PMC286587/ https://ncbi.nlm.nih.gov/pubmed/2644651 https://ncbi.nlm.nih.gov/pmc/articles/PMC286588/ https://ncbi.nlm.nih.gov/pubmed/2492666 https://ncbi.nlm.nih.gov/pmc/articles/PMC286589/ https://ncbi.nlm.nih.gov/pubmed/2536936 https://ncbi.nlm.nih.gov/pmc/articles/PMC286590/ https://ncbi.nlm.nih.gov/pubmed/2536937 https://ncbi.nlm.nih.gov/pmc/articles/PMC286591/ https://ncbi.nlm.nih.gov/pubmed/2915986 https://ncbi.nlm.nih.gov/pmc/articles/PMC286592/ https://ncbi.nlm.nih.gov/pubmed/2915987 https://ncbi.nlm.nih.gov/pmc/articles/PMC286593/ https://ncbi.nlm.nih.gov/pubmed/2915988 https://ncbi.nlm.nih.gov/pmc/articles/PMC286594/ https://ncbi.nlm.nih.gov/pubmed/2644652 https://ncbi.nlm.nih.gov/pmc/articles/PMC286595/ https://ncbi.nlm.nih.gov/pubmed/2492667 https://ncbi.nlm.nih.gov/pmc/articles/PMC286596/ https://ncbi.nlm.nih.gov/pubmed/2536938 https://ncbi.nlm.nih.gov/pmc/articles/PMC286597/ https://ncbi.nlm.nih.gov/pubmed/2915989
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Identification of the convulsant opiate thebaine in mammalian brain.

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