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Nonanesthetic alcohols dissolve in synaptic membranes without perturbing their lipids.

While many theories of general anesthesia postulate a lipid site of action, there has been no adequate explanation for the lack of anesthetic potency of the highly hydrophobic primary alkanols with more than 12 carbons (the cut-off). Some work suggests that these nonanesthetic alcohols do not dissol...

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Detalhes bibliográficos
Main Authors: Miller, K W, Firestone, L L, Alifimoff, J K, Streicher, P
Formato: Artigo
Idioma:en
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC286626/
https://ncbi.nlm.nih.gov/pubmed/2783782
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