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Characterization of oligonucleotide transport into living cells.

Addition of antisense oligonucleotides to cell cultures has been used to specifically inhibit gene expression. We have investigated the mechanism by which oligonucleotides enter living cells. These compounds are taken up by cells in a saturable, size-dependent manner compatible with receptor-mediate...

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Detalhes bibliográficos
Main Authors: Loke, S L, Stein, C A, Zhang, X H, Mori, K, Nakanishi, M, Subasinghe, C, Cohen, J S, Neckers, L M
Formato: Artigo
Idioma:en
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC287160/
https://ncbi.nlm.nih.gov/pubmed/2726730
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