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Synergistic and Antagonistic Interactions between Tetrodotoxin and μ-Conotoxin in Blocking Voltage-gated Sodium Channels
Tetrodotoxin (TTX) is the quintessential ligand of voltage-gated sodium channels (Na(V)s). Like TTX, μ-conotoxin peptides are pore blockers, and both toxins have helped to define the properties of neurotoxin receptor Site 1 of Na(V)s. Here, we report unexpected results showing that the recently disc...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878737/ https://ncbi.nlm.nih.gov/pubmed/19221510 |
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