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Deletion of the donor splice site of intron 4 in the glucokinase gene causes maturity-onset diabetes of the young.
Missense and nonsense mutations in the glucokinase gene have recently been shown to result in maturity-onset diabetes of the young (MODY), a subtype of non-insulin-dependent diabetes mellitus with early age of onset. Glucokinase catalyzes the formation of glucose-6-phosphate and is involved in the r...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | en |
| Publicado em: |
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC288255/ https://ncbi.nlm.nih.gov/pubmed/8376578 |
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