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Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM receptor Tyro3 and sphingosine 1-phosphate receptor
The anticoagulant factor protein S (PS) has direct cellular activities. Lack of PS in mice causes lethal coagulopathy, ischemic/thrombotic injuries, vascular dysgenesis, and blood-brain barrier (BBB) disruption with intracerebral hemorrhages. Thus, we hypothesized that PS maintains and/or enhances t...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
American Society of Hematology
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890172/ https://ncbi.nlm.nih.gov/pubmed/20348395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-262386 |
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