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Substrate-induced Changes in Protease Active Site Conformation Impact on Subsequent Reactions with Substrates

Enzymatic catalysis of biochemical reactions is essential to all living systems. The “lock and key” and “induced fit” models were early contributions to our understanding of the mechanisms involved in the reaction between an enzyme and its substrate. However, whether a given substrate-induced confor...

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Formato: Artigo
Idioma:en
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906288/
https://ncbi.nlm.nih.gov/pubmed/20484054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.103549
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