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Selective Incision of the α-N(5)-Methyl-Formamidopyrimidine Anomer by Escherichia coli Endonuclease IV
Formamidopyrimidines (Fapy) lesions result from ring opening of the imidazole portion of purines. Fapy lesions can isomerize from the natural β-anomeric stereochemistry to the α-configuration. We have unambiguously demonstrated that the α-methyl-Fapy-dG (MeFapy-dG) lesion is a substrate for Escheric...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
SAGE-Hindawi Access to Research
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2925382/ https://ncbi.nlm.nih.gov/pubmed/20798848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/850234 |
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