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Protein kinase C is increased in the liver of humans and rats with non-insulin-dependent diabetes mellitus: an alteration not due to hyperglycemia.

We tested the hypothesis that liver protein kinase C (PKC) is increased in non-insulin-dependent diabetes mellitus (NIDDM). To this end we examined the distribution of PKC isozymes in liver biopsies from obese individuals with and without NIDDM and in lean controls. PKC isozymes alpha, beta, epsilon...

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Main Authors:	Considine, R V, Nyce, M R, Allen, L E, Morales, L M, Triester, S, Serrano, J, Colberg, J, Lanza-Jacoby, S, Caro, J F, Watanabe, M, Ueno, Y, Yajima, T, Iwao, Y, Tsuchiya, M, Ishikawa, H, Aiso, S, Hibi, T, Ishii, H, Utans, U, Arceci, R J, Yamashita, Y, Russell, M E, Deterding, R R, Shannon, J M, Nichol, J L, Hokom, M M, Hornkohl, A, Sheridan, W P, Ohashi, H, Kato, T, Li, Y S, Bartley, T D, Choi, E, Bogenberger, J, Healey, D, Ozegbe, P, Arden, S, Chandler, P, Hutton, J, Cooke, A, Considine, E L, Williams, C J, Magosin, S A, Bauer, T L, Rosato, E L, Harris, H W, Strange, K, Zeidel, M L, Lehr, H A, Hübner, C, Finckh, B, Angermüller, S, Nolte, D, Beisiegel, U, Kohlschütter, A, Messmer, K, Movsesian, M A, Smith, C J, Krall, J, Bristow, M R, Manganiello, V C, Dobrina, A, Menegazzi, R, Carlos, T M, Nardon, E, Cramer, R, Zacchi, T, Harlan, J M, Patriarca, P, Tessari, P, Inchiostro, S, Biolo, G, Vincenti, E, Sabadin, L, Alexander, H R, Sheppard, B C, Jensen, J C, Langstein, H N, Buresh, C M, Venzon, D, Walker, E C, Fraker, D L, Stovroff, M C, Norton, J A, Piedimonte, G, McDonald, D M, Nadel, J A, Xie, M S, Jacobs, L S, Dubyak, G R, Ikenouchi, H, Kohmoto, O, McMillan, M, Barry, W H, Bataille, R, Chappard, D, Marcelli, C, Dessauw, P, Baldet, P, Sany, J, Alexandre, C, Levitt, L J, Nagler, A, Lee, F, Abrams, J, Shatsky, M, Thompson, D, Garbarz, M, Tse, W T, Gallagher, P G, Picat, C, Lecomte, M C, Galibert, F, Dhermy, D, Forget, B G, Sadziene, A, Thomas, D D, Bundoc, V G, Holt, S C, Barbour, A G, Lichtenstein, A, Pelayo, J C, Westcott, J Y, Brown, T R, Sundick, R S, Dhar, A, Sheth, D, Bagchi, N, Kim, N, Azadzoi, K M, Goldstein, I, Saenz de Tejada, I, Pothoulakis, C, LaMont, J T, Eglow, R, Gao, N, Rubins, J B, Theoharides, T C, Dickey, B F, Bastani, B, Purcell, H, Hemken, P, Trigg, D, Gluck, S, Sands, J M, Schrader, D C, Quiding, M, Nordström, I, Kilander, A, Andersson, G, Hanson, L A, Holmgren, J, Czerkinsky, C, Ruiz, P, Gomez, F, King, M, Lopez, R, Darby, C, Schreiber, A D, Myers, S R, Biggers, D W, Neal, D W, Cherrington, A D, Swinburn, B A, Nyomba, B L, Saad, M F, Zurlo, F, Raz, I, Knowler, W C, Lillioja, S, Bogardus, C, Ravussin, E, Mahoney, S E, Duvic, M, Nickoloff, B J, Minshall, M, Smith, L C, Griffiths, C E, Paddock, S W, Lewis, D E, Chapman, P B, Houghton, A N, Olee, T, Yang, P M, Siminovitch, K A, Olsen, N J, Hillson, J, Wu, J, Kozin, F, Carson, D A, Chen, P P, Rocha-Singh, K J, Honbo, N Y, Karliner, J S, Ferrari, C, Bertoletti, A, Penna, A, Cavalli, A, Valli, A, Missale, G, Pilli, M, Fowler, P, Giuberti, T, Chisari, F V, Akashi, K, Shibuya, T, Harada, M, Takamatsu, Y, Uike, N, Eto, T, Niho, Y, Freedman, D O, Lujan-Trangay, A, Steel, C, Gonzalez-Peralta, C, Nutman, T B, Tanner, J, Tosato, G, Fujihashi, K, McGhee, J R, Lue, C, Beagley, K W, Taga, T, Hirano, T, Kishimoto, T, Mestecky, J, Kiyono, H, Rand, J H, Patel, N D, Schwartz, E, Zhou, S L, Potter, B J, Lu, S C, Kuhlenkamp, J, Garcia-Ruiz, C, Kaplowitz, N, Linton, M F, Gish, R, Hubl, S T, Bütler, E, Esquivel, C, Bry, W I, Boyles, J K, Wardell, M R, Young, S G, Maio, M, Altomonte, M, Tatake, R, Zeff, R A, Ferrone, S, Sié, P, Bezeaud, A, Dupouy, D, Archipoff, G, Freyssinet, J M, Dugoujon, J M, Serre, G, Guillin, M C, Boneu, B, Jaffe, H A, Buhl, R, Mastrangeli, A, Holroyd, K J, Saltini, C, Czerski, D, Jaffe, H S, Kramer, S, Sherwin, S, Crystal, R G, Lien, Y H, Shapiro, J I, Chan, L, Bunchman, T E, Brookshire, C A, Fairley, J A, Scott, G A, Jensen, K D, Goldsmith, L A, Diaz, L A
Formato:	Artigo
Idioma:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
Publicado em:	1995
Assuntos:	Research Article Correction
Acesso em linha:	https://ncbi.nlm.nih.gov/pmc/articles/PMC295982/ https://ncbi.nlm.nih.gov/pubmed/7769136 https://ncbi.nlm.nih.gov/pmc/articles/PMC295983/ https://ncbi.nlm.nih.gov/pubmed/7769137 https://ncbi.nlm.nih.gov/pmc/articles/PMC295984/ https://ncbi.nlm.nih.gov/pubmed/7769138 https://ncbi.nlm.nih.gov/pmc/articles/PMC295985/ https://ncbi.nlm.nih.gov/pubmed/7769139 https://ncbi.nlm.nih.gov/pmc/articles/PMC295986/ https://ncbi.nlm.nih.gov/pubmed/7539462 https://ncbi.nlm.nih.gov/pmc/articles/PMC295987/ https://ncbi.nlm.nih.gov/pubmed/7769140 https://ncbi.nlm.nih.gov/pmc/articles/PMC295988/ https://ncbi.nlm.nih.gov/pubmed/7769141 https://ncbi.nlm.nih.gov/pmc/articles/PMC295989/ https://ncbi.nlm.nih.gov/pmc/articles/PMC295994/ https://ncbi.nlm.nih.gov/pubmed/2056113 https://ncbi.nlm.nih.gov/pmc/articles/PMC295995/ https://ncbi.nlm.nih.gov/pubmed/2056134 https://ncbi.nlm.nih.gov/pmc/articles/PMC295996/ https://ncbi.nlm.nih.gov/pubmed/1647414 https://ncbi.nlm.nih.gov/pmc/articles/PMC295997/ https://ncbi.nlm.nih.gov/pubmed/1711540 https://ncbi.nlm.nih.gov/pmc/articles/PMC295998/ https://ncbi.nlm.nih.gov/pubmed/2056121 https://ncbi.nlm.nih.gov/pmc/articles/PMC295999/ https://ncbi.nlm.nih.gov/pubmed/2056127 https://ncbi.nlm.nih.gov/pmc/articles/PMC296000/ https://ncbi.nlm.nih.gov/pubmed/1711545 https://ncbi.nlm.nih.gov/pmc/articles/PMC296001/ https://ncbi.nlm.nih.gov/pubmed/1905330 https://ncbi.nlm.nih.gov/pmc/articles/PMC296002/ https://ncbi.nlm.nih.gov/pubmed/2056130 https://ncbi.nlm.nih.gov/pmc/articles/PMC296003/ https://ncbi.nlm.nih.gov/pubmed/2056131 https://ncbi.nlm.nih.gov/pmc/articles/PMC296004/ https://ncbi.nlm.nih.gov/pubmed/1676038 https://ncbi.nlm.nih.gov/pmc/articles/PMC296005/ https://ncbi.nlm.nih.gov/pubmed/2056132 https://ncbi.nlm.nih.gov/pmc/articles/PMC296006/ https://ncbi.nlm.nih.gov/pubmed/2056133 https://ncbi.nlm.nih.gov/pmc/articles/PMC296007/ https://ncbi.nlm.nih.gov/pubmed/2056135 https://ncbi.nlm.nih.gov/pmc/articles/PMC296008/ https://ncbi.nlm.nih.gov/pubmed/2056114 https://ncbi.nlm.nih.gov/pmc/articles/PMC296009/ https://ncbi.nlm.nih.gov/pubmed/1647412 https://ncbi.nlm.nih.gov/pmc/articles/PMC296010/ https://ncbi.nlm.nih.gov/pubmed/1647413 https://ncbi.nlm.nih.gov/pmc/articles/PMC296011/ https://ncbi.nlm.nih.gov/pubmed/1905325 https://ncbi.nlm.nih.gov/pmc/articles/PMC296012/ https://ncbi.nlm.nih.gov/pubmed/1829094 https://ncbi.nlm.nih.gov/pmc/articles/PMC296013/ https://ncbi.nlm.nih.gov/pubmed/1905326 https://ncbi.nlm.nih.gov/pmc/articles/PMC296014/ https://ncbi.nlm.nih.gov/pubmed/1905327 https://ncbi.nlm.nih.gov/pmc/articles/PMC296015/ https://ncbi.nlm.nih.gov/pubmed/1829095 https://ncbi.nlm.nih.gov/pmc/articles/PMC296016/ https://ncbi.nlm.nih.gov/pubmed/2056115 https://ncbi.nlm.nih.gov/pmc/articles/PMC296017/ https://ncbi.nlm.nih.gov/pubmed/2056116 https://ncbi.nlm.nih.gov/pmc/articles/PMC296018/ https://ncbi.nlm.nih.gov/pubmed/1676036 https://ncbi.nlm.nih.gov/pmc/articles/PMC296019/ https://ncbi.nlm.nih.gov/pubmed/2056117 https://ncbi.nlm.nih.gov/pmc/articles/PMC296020/ https://ncbi.nlm.nih.gov/pubmed/1676037 https://ncbi.nlm.nih.gov/pmc/articles/PMC296021/ https://ncbi.nlm.nih.gov/pubmed/1647415 https://ncbi.nlm.nih.gov/pmc/articles/PMC296022/ https://ncbi.nlm.nih.gov/pubmed/1711541 https://ncbi.nlm.nih.gov/pmc/articles/PMC296023/ https://ncbi.nlm.nih.gov/pubmed/2056118 https://ncbi.nlm.nih.gov/pmc/articles/PMC296024/ https://ncbi.nlm.nih.gov/pubmed/1829096 https://ncbi.nlm.nih.gov/pmc/articles/PMC296025/ https://ncbi.nlm.nih.gov/pubmed/1647416 https://ncbi.nlm.nih.gov/pmc/articles/PMC296026/ https://ncbi.nlm.nih.gov/pubmed/2056119 https://ncbi.nlm.nih.gov/pmc/articles/PMC296027/ https://ncbi.nlm.nih.gov/pubmed/2056120 https://ncbi.nlm.nih.gov/pmc/articles/PMC296028/ https://ncbi.nlm.nih.gov/pubmed/1647417 https://ncbi.nlm.nih.gov/pmc/articles/PMC296029/ https://ncbi.nlm.nih.gov/pubmed/2056122 https://ncbi.nlm.nih.gov/pmc/articles/PMC296030/ https://ncbi.nlm.nih.gov/pubmed/1905328 https://ncbi.nlm.nih.gov/pmc/articles/PMC296031/ https://ncbi.nlm.nih.gov/pubmed/1711542 https://ncbi.nlm.nih.gov/pmc/articles/PMC296032/ https://ncbi.nlm.nih.gov/pubmed/1905329 https://ncbi.nlm.nih.gov/pmc/articles/PMC296033/ https://ncbi.nlm.nih.gov/pubmed/2056123 https://ncbi.nlm.nih.gov/pmc/articles/PMC296034/ https://ncbi.nlm.nih.gov/pubmed/2056124 https://ncbi.nlm.nih.gov/pmc/articles/PMC296035/ https://ncbi.nlm.nih.gov/pubmed/1711543
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Protein kinase C is increased in the liver of humans and rats with non-insulin-dependent diabetes mellitus: an alteration not due to hyperglycemia.

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