Human Immunodeficiency Virus Type 1 Fitness Is a Determining Factor in Viral Rebound and Set Point in Chronic Infection

Human immunodeficiency virus type 1 (HIV-1) isolates from 20 chronically infected patients who participated in a structured treatment interruption (STI) trial were studied to determine whether viral fitness influences reestablishment of viremia. Viruses derived from individuals who spontaneously con...

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Main Authors: Trkola, Alexandra, Kuster, Herbert, Leemann, Christine, Ruprecht, Claudia, Joos, Beda, Telenti, Amalio, Hirschel, Bernhard, Weber, Rainer, Bonhoeffer, Sebastian, Günthard, Huldrych F., Pereira, Lenore, Maidji, Ekaterina, McDonagh, Susan, Genbacev, Olga, Fisher, Susan, Crowther, R. A., Berriman, J. A., Curran, W. L., Allan, G. M., Todd, D., Besnier, Caroline, Ylinen, Laura, Strange, Benjamin, Lister, Adrian, Takeuchi, Yasuhiro, Goff, Stephen P., Towers, Greg J., Hagglund, Ryan, Roizman, Bernard, Zhao, Lisa Y., Liao, Daiqing, Izumi, Yasuyuki, Ami, Yasushi, Matsuo, Kazuhiro, Someya, Kenji, Sata, Tetsutaro, Yamamoto, Naoki, Honda, Mitsuo, Brunetti, Craig R., Amano, Hiroko, Ueda, Yoshiaki, Qin, Jing, Miyamura, Tatsuo, Suzuki, Tetsuro, Li, Xing, Barrett, John W., McFadden, Grant, Dumonceaux, Julie, Cormier, Emmanuel G., Kajumo, Francis, Donovan, Gerald P., Roy-Chowdhury, Jayanta, Fox, Ira J., Gardner, Jason P., Dragic, Tatjana, Donelan, Nicola R., Basler, Christopher F., García-Sastre, Adolfo, Sanchez, Veronica, McElroy, Anita K., Spector, Deborah H., Rubin, Steven A., Amexis, Georgios, Pletnikov, Mikhail, Li, Zongqi, Vanderzanden, Jacqueline, Mauldin, Jeremy, Sauder, Christian, Malik, Tahir, Chumakov, Konstantin, Carbone, Kathryn M., Rodriguez, Jason J., Wang, Lin-Fa, Horvath, Curt M., Thurn, K K, Chatterjee, A K, Kitamura, M, Taylor, S, Unwin, R, Burton, S, Shimizu, F, Fine, L G, Adams, M, Matthews, C, Collingwood, T N, Tone, Y, Beck-Peccoz, P, Chatterjee, K K, Fanen, P, Guidoux, S, Sarde, C O, Mandel, J L, Goossens, M, Aubourg, P, Merino, R, Iwamoto, M, Gershwin, M E, Izui, S, Fournier, B, Saudubray, J M, Benichou, B, Lyonnet, S, Munnich, A, Clevers, H, Poll-The, B T, Irigoyen, M, Manheimer-Lory, A, Gaynor, B, Diamond, B, Vollmar, A M, Schulz, R, Beitel, L K, Kazemi-Esfarjani, P, Kaufman, M, Lumbroso, R, DiGeorge, A M, Killinger, D W, Trifiro, M A, Pinsky, L, Vernet-der Garabedian, B, Lacokova, M, Eymard, B, Morel, E, Faltin, M, Zajac, J, Sadovsky, O, Dommergues, M, Tripon, P, Bach, J F, Huang, R, Rosenbach, M, Vaughn, R, Provvedini, D, Rebbe, N, Hickman, S, Goding, J, Terkeltaub, R, Kramers, C, Hylkema, M N, van Bruggen, M C, van de Lagemaat, R, Dijkman, H B, Assmann, K J, Smeenk, R J, Berden, J H, Kouyoumdjian, C, Adnot, S, Levame, M, Eddahibi, S, Bousbaa, H, Raffestin, B, Finck, B K, Chan, B, Wofsy, D, Faruqi, R, de la Motte, C, DiCorleto, P E, Higuchi, I, Yamada, H, Fukunaga, H, Iwaki, H, Okubo, R, Nakagawa, M, Osame, M, Roberds, S L, Shimizu, T, Campbell, K P, Hayashi, Y, Sunthornthepvarakul, T, Refetoff, S, Hollenbaugh, D, Wu, L H, Ochs, H D, Nonoyama, S, Grosmaire, L S, Ledbetter, J A, Noelle, R J, Hill, H, Aruffo, A, Harada, K, Grossman, W, Friedman, M, Edelman, E R, Prasad, P V, Keighley, C S, Manning, W J, Sellke, F W, Simons, M, Patel, K D, Modur, V, Zimmerman, G A, Prescott, S M, McIntyre, T M, Hassoun, H, Coetzer, T L, Vassiliadis, J N, Sahr, K E, Maalouf, G J, Saad, S T, Catanzariti, L, Palek, J, Cable, E E, Pepe, J A, Karamitsios, N C, Lambrecht, R W, Bonkovsky, H L, Wahl, S M, Allen, J B, Hines, K L, Imamichi, T, Wahl, A M, Furcht, L T, McCarthy, J B, Pittet, J F, Wiener-Kronish, J P, McElroy, M C, Folkesson, H G, Matthay, M A, Levy, O, Ooi, C E, Weiss, J, Lehrer, R I, Elsbach, P, Corbett, J D, Agre, P, Golan, D E, Kuruvilla, A G, D'Souza, S W, Glazier, J D, Mahendran, D, Maresh, M J, Sibley, C P, Slotkin, T A, Nemeroff, C B, Bissette, G, Seidler, F J, Dabholkar, M, Vionnet, J, Bostick-Bruton, F, Yu, J J, Reed, E, Ståhl-Hallengren, C, Ukkonen, T, Kainulainen, K, Kristofersson, U, Saxne, T, Tornqvist, K, Peltonen, L, Yang, X, Chowdhury, N, Cai, B, Brett, J, Marboe, C, Sciacca, R R, Michler, R E, Cannon, P J, Russell, M E, Utans, U, Wallace, A F, Liang, P, Arceci, R J, Karnovsky, M J, Wyner, L R, Yamashita, Y, Tarn, C, Crestani, B, Cornillet, P, Dehoux, M, Rolland, C, Guenounou, M, Aubier, M, Benders, A A, Veerkamp, J H, Oosterhof, A, Jongen, P J, Bindels, R J, Smit, L M, Busch, H F, Wevers, R A, Cope, A P, Londei, M, Chu, N R, Cohen, S B, Elliott, M J, Brennan, F M, Maini, R N, Feldmann, M, Howe, S, Eaker, E Y, Sallustio, J E, Peebles, C, Tan, E M, Williams, R C, Kawamura, M, Heinecke, J W, Chait, A
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Publicado em: American Society for Microbiology 2003
Assuntos:
Vaccines and Antiviral Agents
Pathogenesis and Immunity
Structure and Assembly
Virus-Cell Interactions
Transformation and Oncogenesis
Recombination and Evolution
Erratum
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC296087/
https://ncbi.nlm.nih.gov/pubmed/14645571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.24.13146-13155.2003
https://ncbi.nlm.nih.gov/pmc/articles/PMC296088/
https://ncbi.nlm.nih.gov/pubmed/14645586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.24.13301-13314.2003
https://ncbi.nlm.nih.gov/pmc/articles/PMC296089/
https://ncbi.nlm.nih.gov/pubmed/14645560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.24.13036-13041.2003
https://ncbi.nlm.nih.gov/pmc/articles/PMC296090/
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https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.24.13403-13406.2003
https://ncbi.nlm.nih.gov/pmc/articles/PMC296091/
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https://ncbi.nlm.nih.gov/pmc/articles/PMC296092/
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https://ncbi.nlm.nih.gov/pmc/articles/PMC296156/
https://ncbi.nlm.nih.gov/pubmed/8040331
https://ncbi.nlm.nih.gov/pmc/articles/PMC296157/
https://ncbi.nlm.nih.gov/pubmed/8040332
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https://ncbi.nlm.nih.gov/pmc/articles/PMC296087/
https://ncbi.nlm.nih.gov/pubmed/14645571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.24.13146-13155.2003
https://ncbi.nlm.nih.gov/pmc/articles/PMC296088/
https://ncbi.nlm.nih.gov/pubmed/14645586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.24.13301-13314.2003
https://ncbi.nlm.nih.gov/pmc/articles/PMC296089/
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https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.24.13036-13041.2003
https://ncbi.nlm.nih.gov/pmc/articles/PMC296090/
https://ncbi.nlm.nih.gov/pubmed/14645596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.24.13403-13406.2003
https://ncbi.nlm.nih.gov/pmc/articles/PMC296091/
https://ncbi.nlm.nih.gov/pubmed/14645576
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https://ncbi.nlm.nih.gov/pubmed/8040330
https://ncbi.nlm.nih.gov/pmc/articles/PMC296156/
https://ncbi.nlm.nih.gov/pubmed/8040331
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