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The 3' untranslated region of the human interferon-beta mRNA has an inhibitory effect on translation.

In vitro-transcribed human interferon-beta (IFN-beta) mRNA, which contains all the sequence of the natural molecule, is poorly translated in a reticulocyte lysate or when injected in Xenopus oocytes. This low level of translation is due to an inhibition by the 5' and 3' untranslated region...

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Detalhes bibliográficos
Main Authors: Kruys, V, Wathelet, M, Poupart, P, Contreras, R, Fiers, W, Content, J, Huez, G
Formato: Artigo
Idioma:en
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC299001/
https://ncbi.nlm.nih.gov/pubmed/3476924
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