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M(3)-muscarinic receptor promotes insulin release via receptor phosphorylation/arrestin-dependent activation of protein kinase D1
The activity of G protein-coupled receptors is regulated via hyper-phosphorylation following agonist stimulation. Despite the universal nature of this regulatory process, the physiological impact of receptor phosphorylation remains poorly studied. To address this question, we have generated a knock-...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
National Academy of Sciences
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3000281/ https://ncbi.nlm.nih.gov/pubmed/21078968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011651107 |
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