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HLA-DP, HLA-DQ, and HLA-DR Have Different Requirements for Invariant Chain and HLA-DM

The MHC is central to the adaptive immune response. The human MHC class II is encoded by three different isotypes, HLA-DR, -DQ, and -DP, each being highly polymorphic. In contrast to HLA-DR, the intracellular assembly and trafficking of HLA-DP molecules have not been studied extensively. However, di...

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Formato: Artigo
Idioma:en
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003381/
https://ncbi.nlm.nih.gov/pubmed/20959457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.148155
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